: Severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters: pooled analysis of national prospective cohort studies of 30 million individuals in England, Northern Ireland, Scotland, and Wales This UK-wide population-based investigation of millions of people in England, Northern Ireland, Scotland, and Wales has found that, after the first vaccine . In this national cohort study, we used a dataset compiled by the National Maternity and Perinatal Audit that was based on records of each birth from maternity information systems used by NHS maternity services in England to record care throughout pregnancy and birth. Participants 4 186 615 singleton live births in Sweden during 1973-2014. . Ethics and dissemination Ethical approval was received from the NSW Population Health Services Research Ethics Committee for the NSW cohort study (Reference: 2022/ETH00382/2022.07) and from the Macquarie University ethics committee for the national cohort study (Reference: 520221151437084). the study outcomes derived for the cohort identified by the maternity episode included fetal death at or beyond 24 weeks' gestation (stillbirth), preterm birth (less than 37 weeks, liveborn or stillborn), small for gestational age at birth (sga; defined as birthweight at the <tenth centile using the united kingdom-world health organization To address these knowledge gaps, we conducted a national cohort study of over 4 million people in Sweden. The study cohort comprised all people born in Denmark between Jan 1, 1980, and Dec 31, 1984, who were residing in the country at their tenth birthday and who had two Danish-born parents. Findings from case-control and cohort studies were judged to be of limited clinical relevance because of their small sample sizes and because between-study comparisons are hampered by substantial differences in methodology and follow-up duration. Our cohorts consisted of individuals aged 18 years and older who had completed their primary vaccine schedule (first and second doses) with BNT162b2 or ChAdOx1 nCoV-19 vaccines only or had subsequent booster doses of BNT162b2 or mRNA-1273 vaccines between Dec 8, 2020, and Feb 28, 2022. In short, a national birth cohort study is essential for developing evidence-based policies that are capable of improving the United States' international health standingand ensuring that every member of the U.S. population has an equal opportunity to thrive. Participants 4 186 615 singleton live births in Sweden during 1973-2014. Neurological manifestations of SARS-CoV-2 infection in hospitalised children and adolescents in the UK: a prospective national cohort study Summary Background The spectrum of neurological and psychiatric complications associated with paediatric SARS-CoV-2 infection is poorly understood. 13 22-29 31 Five of the studies are though similar to ours, based . 10 ; More than 400 projects are underway using the enclave data to examine associations . Setting up of this cohort of patients and relatives will provide the best resource for understanding what causes or triggers the disease, how to predict risk . Objective To investigate the relation between preterm birth (gestational age <37 weeks) and risk of CKD from childhood into mid-adulthood. Setting Sweden. 2019;53(22):1405-1411. Sociodemographic Characteristics at Baseline (2000-2001) eTable 2. Objectives To follow up a UK national cohort of women admitted to hospital with confirmed 2009/H1N1 influenza in pregnancy in order to obtain a complete picture of pregnancy outcomes and estimate the risks of adverse fetal and infant outcomes. The hospital is the largest . Gulf War Follow-up Study. Methods We included all Medicare enrollees 65 years and older in the fee-for-service program, part A and part B, in the contiguous United States (2000-2016). This is the first such study to collect in-depth clinical information for a national cohort of patients who accessed Dutch hospices. Participants: All 2 437 718 individuals live born in Denmark, 1978-2018, with follow-up from date of birth until date of death . Methods for a National Birth Cohort Study By Greg Duncan, Virginia Lesser, Barbara Entwisle, Graham Kalton, Andy Shih, Elaine Faustman, Rosalind Wright, Kerry Anne McGeary, Richard Gershon, Steven Wysmuller, Shelley Merritt, and Charlee Alexander May 31, 2016 | Discussion Paper The cohort was established by identifying all patients with the first diagnosis of T2DM in the National Health Insurance Fund database during 2000-2012. Furthermore, even if the incidence of homicide perpetration among people with serious . Agrawal et al. Setting: Danish national health registers. Purpose This study aimed to investigate the association between metformin usage and the risk of colorectal cancer (CRC) using data from the Korean National Health Insurance Service-National Health Screening Cohort database. Objectives The purpose of this study is to evaluate the risk of retropharyngeal and parapharyngeal abscesses (deep neck infection) after tonsillectomy in Koreans using national cohort data. Sex Differences in Treatments, Relative Survival, and Excess Mortality Following Acute Myocardial Infarction: National Cohort Study Using the SWEDEHEART Registry. A follow-up study of this same cohort of CMT trainees reported on the relationship between the selection methods used and subsequent performance at postgraduate membership exams.9 The authors reported that the clinical problem solving test and SJT scores explained an additional 6.3%-21.6% of the variance in performance on the membership exams . Our national register-based cohort study of almost 63 000 people discharged from inpatient psychiatric care indicates higher risk for perpetrating than for becoming a victim of homicide in this population, albeit with very low absolute risks for both outcomes. ; The public-facing N3C Dashboards provide high-level information about the N3C cohort and N3C Data Enclave. 14 this system entails active surveillance with reporting from all 194 hospitals in the uk with a consultant led maternity unit and includes well established routines to secure complete reporting. Listing a study does not mean it has been evaluated by the U.S. Federal Government. We examined national registry data to evaluate the association between post-stroke functional level and the risk of low falls among post-stroke patients. National COVID Cohort Collaborative (N3C) Data Enclave. The results of this study will help VA to better understand . This positive association was also confirmed by findings in a meta-analysis of 30 cohort studies in multiple populations. In this explorative study, we address that shortcoming by using a large cohort sample (fifteen national cohorts, over 1.5 million children) and data from several Swedish national registers to examine the influence of parental background factors on the risk of children entering out-of-home (state/public) care in foster-homes or residential units. A retrospective cohort design was used with the objective to evaluate cancer risk among people with type 2 diabetes mellitus (T2DM) in Lithuania. Researchers pilot plans for new national birth cohort study 13 May 2021 Researchers are set to test innovative approaches to a major new UK-wide study that will follow babies born in the 2020s over many decades. Read our disclaimer for details. Employ tracking resources, such as telephone directories, the US Postal Service's National Change of Address system, or Internet tracking resources. Exposures Gestational age at birth, identified from nationwide birth records in the Swedish birth registry. Gout and the risk of advanced chronic kidney disease in the UK health system: a national cohort study Austin G Stack 1, Michelle Elizabeth Johnson 2, Betina Blak 3, Alyssa Klein 4, Lewis Carpenter 2, Robert Morlock 5, Andrew R Maguire 2, Victoria L Parsons 2 Correspondence to Dr Austin G Stack; austin.stack@ul.ie Abstract Stroke patients have increased risks of falls. To this end, 36 German Academic Medical Centers started to collaborate on 13 projects, with the largest being the National Pandemic Cohort Network (NAPKON). Objective: To examine the association of maternal hypertensive disorder of pregnancy (HDP) with overall and cause specific mortality in offspring from birth to young adulthood. The goals of this study were to examine associations between gestational age at birth and risk of type 1 or type 2 diabetes up to age 43 years, the maximum follow-up currently possible in this large cohort, to assess whether these . 15 information about women who died or who had | Find, read and cite all the research you . Hazard Ratios for Association Between Bipolar Disorder (2001-2002) and Diagnosis With Selected Conditions (2003-2009) eTable 3. Piercy KL, Troiano RP, Ballard RM, They are a type of longitudinal study design. Methods Data from the NHIS-HEALS cohort between 2002 and 2015 were longitudinally analyzed. Design National cohort study. The cohort was established on the basis of data obtained from seven Swedish national registers. The "SKin and soft tissue INfections in the ICU" (SKIN-ICU) study is a multinational prospective non-interventional cohort study that will include patients with NSTI admitted or not to the ICU/intermediate care unit and aim at addressing the following points: 1) Hospital (i.e., ICU and hospital mortality) and medium-term outcomes (three- and . National Cohort Study of Idiopathic and Heritable PAH Idiopathic and heritable forms of pulmonary arterial hypertension (PAH) are devastating conditions associated with high morbidity and mortality. We have conducted the first large-scale, national cohort study of early growth in ART children from birth to school age, linking the register of ART, held by the UK's Human Fertilisation and Embryology Authority, to Scottish maternity and child health databases. Standardized Mortality Ratios for Association Between Bipolar Disorder (2001-2002) and Selected Cause-Specific Mortality (2003-2008) 1. Subjects were divided into three groups: metformin non-users with diabetes . Main outcome measures Incident cases of all cause dementia and . 2 METHODS 2.1 Study design, setting, and period. Results To address these knowledge gaps in studying ADRD incidence in the US, here we constructed a national, population-based cohort study from Medicare data to investigate the impact of long-term. We conducted a nationwide prospective cohort study of 6042 participants (median age 43 years, 50.2% women) in Taiwan's Hypertensive, Hyperglycemia and Hyperlipidemia Survey, of whom 2002 were. PubMedGoogle ScholarCrossref 6. Objective To investigate the association between long term residential exposure to road traffic and railway noise and risk of incident dementia. [15] The registry consists of population-based data containing information on pregnancy, delivery and neonatal outcomes. In this register-based study in a national cohort of young adults, maternal and paternal death from external causes during childhood were associated with a two- to threefold increased risk of hospitalization and outpatient care for depression in men and a 70-100% increase in women. Mammography service screening and breast cancer mortality in New Zealand: a National Cohort Study 1999-2011. Methods: We conducted a retrospective population-based cohort study using the National Health Insurance Research Database of Taiwan from 2001 to 2011 to examine the relationship between aspirin use before hospital admission and sepsis outcomes. The tools were specific to certain study designs and tested for potential flaws in study methods or implementation. Thus, we conducted a retrospective national cohort study to investigate whether Sjogren's syndrome (SS) increases the risk of respiratory failure (RF). 13 The most consistent findings from those studies concern a (transient) delay in motor development . Br J Cancer 116, 828-839 (2017 . Methods and analysis In this setting, the development of a simple and reproducible nutritional checklist is of utmost importance. Setting Denmark. The longer-term mental health impacts of flooding are not well understood. Oras A Alabas, BSc, MSc, PhD, . Objectives Few studies have evaluated the association between Sjogren's syndrome (SS) and respiratory failure (RF). The German government initiated the Network University Medicine (NUM) in early 2020 to improve national research activities on the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic. PDF | The presentation aims to give an overview of design, methods and first results of the German National Cohort (NAKO), the largest cohort study in. Design National cohort study. To inform the public and policy makers, we investigated and compared the risk of cerebral venous sinus thrombosis (CVST) after SARS-Cov-2 vaccination or infection using a national cohort of 2,643,699 individuals aged 17 y and above, alive, and resident in Wales on 1 January 2020 followed up through multiple linked data sources until 28 March 2021. The current survey examines trends in health status over time. Design: Nationwide population based cohort study. Setting 221 hospitals with obstetrician led maternity units in the UK. In 2015, the English National Study of Flooding and Health was established to improve understanding of the impact of flooding on health and inform future public health action. More than 6 million COVID-19-positive patients and more than 19.4 billion rows of data are included in this enclave.Apply for N3C access today. The study will aim to understand how societal circumstances and events affect them. 10 the primary aim of the study reported here was to use information from ukoss to investigate whether differences exist in the incidence of specific Swahn E. Time trends in STEMIimproved treatment and outcome but still a gender gap: a prospective observational cohort study from the SWEDEHEART . This was a retrospective cohort study using data routinely collected for maternity care in the English National Health Service between 1st April 2015 and 31st March 2016. It follows the lives of all people born in England, Scotland and Wales in one particular week of March 1958. Background Flooding is expected to increase due to climate change, population growth and urban development. Save this study Prospective Cohort Study on the Clinical Trajectory of Resected Hepatocellular Carcinoma (PLANET) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Main outcome measures CKD, identified from nationwide inpatient and outpatient diagnoses through 2015 (maximum age 43 years). Conclusions Overall, this large prospective national cohort study comparing the frequency of maternal morbidities of women who had a diagnosis of COVID-19 before or at the time of childbirth with that of pregnant women without diagnosis of COVID-19 who gave birth during the same period suggested an association between COVID-19 and maternal and . more Biomedical data the establishment of the uk obstetric surveillance system (ukoss) has enabled the routine study of severe maternal morbidity on a national population basis for the first time in the united kingdom. Akiskal Setting Sweden. The Taiwan Birth Cohort Study aimed to develop a nationally representative cohort database, with all children born in 2005 eligible to participate, with no exclusion criteria, using a national household probability and a two-stage stratified random sampling method. The purpose of this study is to set up a national cohort of heritable, idiopathic PAH cases, PVOD/PCH and their relatives, to study the genetic and environmental contributions to disease. The aim of this study was to evaluate whether the incidence of oral streptococcal IE increased among high-risk individuals after October 2012. Br J Sports Med. Methods Using the national cohort study from the Korean Health Insurance Review and Assessment Service, participants who had undergone a tonsillectomy (5,299) and control participants (21,196) were selected . In this national population-based cohort study in China, we found that higher SUA levels were associated with an increased risk of incident CKD, independent of other risk factors and consistent across subgroups. National cohort study. 11 13 16 18 22-32 We find that some of these study are not comparable to ours because most of them are case-control studies and with cohorts much smaller than ours. National Cohort Study of Effectiveness and Safety of SARS-CoV-2/COVID-19 Vaccines (ENFORCE) (ENFORCE) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Methods We used 3 years of data from . Participants 1 938 994 adults aged 60 years living in Denmark between 1 January 2004 and 31 December 2017. Results: The overall adjusted vaccine effectiveness against infection decreased from 81.3% (confidence interval (CI): 80.7 to 81.9) in the first 2 to 9 weeks after receiving a second dose to 8.6% (CI: 4.0 to 13.1) after more than 33 weeks, compared to 98.6% (CI: 97.5 to 99.2) and 66.6% (CI: 57.9 to 73.6) against hospitalisation respectively. Several studies have not found an association between exposure to any SSRI and major malformations overall. Methods This nationwide cohort study included all adult individuals (>17 years) living in Sweden from January 2008 to January 2018, with a diagnose code or surgical procedure code indicating high risk of IE. The Danish Data Protection Agency approved the study, with data access agreed by the Health Data Authority and Statistics Denmark. The National COVID Cohort Collaborative The National COVID Cohort Collaborative (N3C, covid.cd2h.org) represents a partnership between the Clinical and Translational Science Awards (CTSA). Data for patients who suffered ischemic strokes and survived the index . Listing a study does not mean it has been evaluated by the U.S. Federal Government. a national, prospective cohort study was conducted using data from the uk obstetric surveillance system. A retrospective cohort study was employed between September 2021 and January 2022 at the Oncology Department of Kenyatta National Hospital. The data for this study were obtained from three population-level electronic datasets, linked together for the purposes of a national audit of maternity care. Cohort studies more clearly indicate the temporal sequence between exposure and outcome, because in a cohort study, subjects are known to be disease-free at the beginning of the observation . Methods The cohort consisted of 4954 newly diagnosed patients with SS but without a previous diagnosis of RF, and 19816 patients . This study was performed in a nationwide cohort using The Netherlands Perinatal Registry (PERINED). The Simple Study is a longitudinal prospective multicentre study aiming to identify the associations between maternal nutritional habits in the first trimester, early markers of placental function and pregnancy outcomes on a large population of singleton pregnancies . Swedish national school register We sincerely appreciate all participants for your support and cooperation. Research findings will be published in peer-reviewed journals and presented at scientific conferences. Study Quality Assessment Tools Study Quality Assessment Tools In 2013, NHLBI developed a set of tailored quality assessment tools to assist reviewers in focusing on concepts that are key to a study's internal validity. Therefore, this study aimed to determine the survival outcomes among colorectal cancer patients at Kenyatta National Hospital. The study was approved by local human ethics committees at the Karolinska Institutet (Stockholm, Sweden) and King's College London (Institute of Psychiatry). Longitudinal studies follow participants over a period of. Cohort studies are a powerful tool for conducting research in human populations. C It describes a patient population that were predominantly of Dutch cultural background, lived alone, had cancer diagnoses and were supported by informal caregivers. We assessed the association between air pollution and first documented diabetes occurrence in a national U.S. cohort of older adults to estimate diabetes risk. The NCDS is a birth cohort study. 3 million adult (aged 19 years), non-immigrant, urban Canadians in 30 cities who responded to the mandatory 2001 Statistics Canada long-form census. The birth sweep collected information about 17,415 newly born babies - an amazing 98 per cent of all the births in Great Britain that week. The Follow-up Study of a National Cohort of Gulf War and Gulf Era Veterans is the third in a series of surveys that examines the health of Veterans who deployed to the Gulf War in 1990-1991 and Veterans who served elsewhere during the same period. Beneficial associations of low and large doses of leisure time physical activity with all-cause, cardiovascular disease and cancer mortality: a national cohort study of 88,140 US adults. This study was supported by grants from the National Natural Science Foundation of China (grant number 81673184). Morrell, S., Taylor, R., Roder, D. et al. In this study, involving more than 16,000 international adoptees in a national cohort of 1,3 million Swedish residents in the ages 6-21 years, we found higher rates of ADHD medication in adopted boys (3.8%) and girls (1.4%), compared with non-adoptees (1.0 and 0.3%, respectively). The NAPKON's goal is creating the . 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